# 使用 Homebrew, Nix 安装 nextflow

查看 nextflow 的安装路径、可执行文件、元数据以及面向 AI 代理工作流的安全说明。

## 安装

```sh
sudo av install brew:nextflow
```

其他安装命令:

### macOS

- Homebrew (100%):

```sh
brew install nextflow
```

  证据: local Homebrew formula metadata

### Linux

- Nix (92%):

```sh
nix profile install nixpkgs#nextflow
```

  证据: nixpkgs package indexes: pkgs/by-name/ne/nextflow/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1

## 软件包事实

- **软件包键:** brew:nextflow
- **软件包管理器:** Homebrew
- **版本:** 26.04.6
- **来源摘要:** Reproducible scientific workflows
- **主页:** <https://nextflow.io>
- **仓库:** <https://github.com/nextflow-io/nextflow>
- **最后更新:** 2026-07-09T22:05:34Z
- **已生成:** 2026-08-03T19:37:03+00:00

## 可执行文件

- nextflow (别名)

## 安装行为

- Bottle: 不可用

## 版本和新鲜度

- 页面生成时间: 2026-08-03
- 管理器版本: 26.04.6
## 项目历史与用法

Nextflow is a workflow system and DSL for scalable, portable, reproducible scientific and data-intensive pipelines. It uses a dataflow programming model, supports containers and environment managers, and can run the same workflow on laptops, HPC schedulers, AWS Batch, Azure Batch, Google Cloud Batch, Kubernetes, and other executors.

### 项目历史

Nextflow was created by Paolo Di Tommaso and collaborators in the computational biology community, then formalized in the 2017 Nature Biotechnology correspondence 'Nextflow enables reproducible computational workflows'. The GitHub README positions it around parallel and distributed pipelines, software dependency isolation, and moving the same pipeline across execution backends.

The project later became closely associated with Seqera and nf-core. nf-core, started in 2018, gave Nextflow a high-quality shared pipeline ecosystem with standards, templates, modules, subworkflows, CI, and community governance. That ecosystem changed Nextflow from a workflow engine into a de facto collaboration format for many bioinformatics groups.

### 采用历史

Nextflow adoption is strongest in bioinformatics, genomics, and research computing, where users need to rerun pipelines across laptops, clusters, and cloud batches without rewriting orchestration. The 2017 Nature Biotechnology article has thousands of citations, and nf-core's 2025 Genome Biology writeup reported 124 pipelines, over 1,400 modules, around 80 subworkflows, 2,600 GitHub contributors, about 1,200 nf-core organization members, and over 10,000 Slack users at publication time.

Homebrew is only one install path; many scientific users install via the bootstrap script, Bioconda, containers, managed HPC modules, or Seqera tooling. Homebrew analytics reported 81 installs in 30 days, 322 in 90 days, and 845 in 365 days for the formula when queried on July 1, 2026.

### 使用方式

Package nerds use nextflow to launch a pipeline repository, pin parameters and profiles in nextflow.config, select an executor, and let Nextflow submit each process to the local machine, a scheduler, cloud batch service, or Kubernetes. The important package behavior is not a single executable doing one task, but a runner that downloads pipeline code, manages work directories, tracks process hashes, resolves containers/environments, and resumes partial runs.

In practice, users often run nf-core pipelines, institutional pipelines, or lab-specific workflows with profiles for Docker, Singularity/Apptainer, Conda, AWS Batch, Slurm, and other environments. The package is a small launcher with a large ecosystem around reproducibility, provenance, workflow sharing, and scientific support.

### 为什么软件包爱好者会关心

Nextflow is one of the major modern scientific workflow engines. In av.db it deserves richer history because package usage often implies access to repositories, tokens, cloud/HPC credentials, container registries, work directories, and config files, not just local command invocation.

### 时间线

- 2013: Nextflow first appeared as an open source workflow project in the early public tag/release history.
- 2017-04-11: Nature Biotechnology published 'Nextflow enables reproducible computational workflows'.
- 2018: nf-core began building a community-curated Nextflow pipeline ecosystem.
- 2025-08-06: nf-core published a Genome Biology community-impact summary covering 2018 through mid-2025.
- 2026-06-17: GitHub page listed Nextflow 26.04.4 as latest stable release.
- 2026-07-01: Homebrew formula version observed as 26.04.4, with 845 formula installs over the preceding 365-day analytics window.

### Related projects

- nf-core
- Seqera Platform
- Bioconda
- Docker
- Singularity/Apptainer
- Conda
- Slurm
- AWS Batch
- Kubernetes

### 来源

- <https://docs.seqera.io/nextflow/executor>
- <https://formulae.brew.sh/api/formula/nextflow.json>
- <https://github.com/nextflow-io/nextflow>
- <https://nf-co.re/blog/2025/paper-v2>
- <https://www.nature.com/articles/nbt.3820>
- <https://www.nextflow.io/about-us.html>


## 安全说明

没有找到 nextflow 的匹配本地密钥处理 manifest。Nucleus 软件包元数据仍在此发布，以便未来覆盖拥有稳定的软件包 URL。



## Configuration and credential file locations

These source-backed paths show where this package keeps local settings or durable credentials. Automic Vault can use them as review targets for secret scanning, migration, and command approval.


## Configuration files

- Unix: nextflow.config, ~/.nextflow/config

## Credential files

- Unix: ~/.nextflow/scm
## 其他软件包管理器记录

- Nix - nextflow: normalized package name match | nixpkgs package indexes: pkgs/by-name/ne/nextflow/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1


## Combined YAML source

View the package source record on GitHub. [combined/nextflow.yml](https://github.com/mxcl/pkgdb/blob/main/combined/nextflow.yml)


## 来源

- pkg.so package database
- Geiger risk classifier
- curated configuration and credential file locations
- curated package history
- pkgdb category and tag curation
- external package-manager database matches
- cross-ecosystem install command graph
