# 使用 Homebrew, Nix, apt 安装 mosdepth 查看 mosdepth 的安装路径、可执行文件、元数据以及面向 AI 代理工作流的安全说明。 ## 安装 ```sh sudo av install brew:mosdepth ``` 其他安装命令: ### macOS - Homebrew (100%): ```sh brew install mosdepth ``` 证据: local Homebrew formula metadata ### Linux - Nix (92%): ```sh nix profile install nixpkgs#mosdepth ``` 证据: nixpkgs package indexes: pkgs/by-name/mo/mosdepth/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1 - Ubuntu apt (92%): ```sh sudo apt install mosdepth ``` 证据: Ubuntu 24.04 LTS package indexes: mosdepth from https://archive.ubuntu.com/ubuntu/dists/noble/universe/binary-amd64/Packages.gz ## 软件包事实 - **软件包键:** brew:mosdepth - **软件包管理器:** Homebrew - **版本:** 0.3.14 - **来源摘要:** Fast BAM/CRAM depth calculation for WGS, exome, or targeted sequencing - **主页:** - **仓库:** - **最后更新:** 2026-07-13T04:04:09Z - **已生成:** 2026-08-03T19:37:03+00:00 ## 可执行文件 - mosdepth (别名) ## 安装行为 - Bottle: 不可用 ## 版本和新鲜度 - 页面生成时间: 2026-08-03 - 管理器版本: 0.3.14 ## 项目历史与用法 mosdepth is a command-line tool for fast BAM/CRAM depth and coverage calculation across whole-genome, exome, or targeted sequencing datasets. ### 项目历史 mosdepth was introduced by Brent S. Pedersen and Aaron R. Quinlan in a Bioinformatics paper published online in October 2017 and appearing in the March 2018 issue. The paper presented it as a quick coverage calculator for genome and exome sequencing data. The implementation is written in Nim and uses HTSlib via hts-nim. Its algorithm tracks alignment chunk starts and ends in chromosome-sized arrays rather than using a pileup engine for every read base. ### 采用历史 mosdepth gained adoption because sequencing coverage summaries are a routine need for variant calling QC, copy-number workflows, targeted panels, exomes, and whole genomes. The paper compared mosdepth with samtools, bedtools, and sambamba and showed faster runtime on a 30x genome benchmark. The official README documents binary releases, Bioconda, Homebrew, and Docker usage, making it straightforward to package in bioinformatics environments and reproducible workflow containers. ### 使用方式 The CLI consumes position-sorted BAM or CRAM input and can report per-base depth, region summaries from BED files, fixed windows, quantized coverage, coverage thresholds, and distributions. Users choose mosdepth when they need fast genome-wide or region-based coverage calculation and can accept the memory profile of chromosome-sized arrays. ### 为什么软件包爱好者会关心 mosdepth is notable to package maintainers because it is a compact compiled bioinformatics binary whose value comes from speed, HTSlib integration, and predictable command-line output files rather than from daemon-style services or configuration. It is also a representative Nim-based scientific CLI in package-manager ecosystems that otherwise contain many C/C++, Python, and Perl genomics tools. ### 时间线 - 2017: Bioinformatics article published online introducing mosdepth. - 2018: Article appears in Bioinformatics volume 34 issue 5. - 2025: GitHub wiki FAQ updated. - 2026: GitHub releases list a latest release dated April 24, 2026. ### Related projects - samtools depth, BEDTools genomecov, and sambamba are related depth/coverage tools compared in the official paper and README. - HTSlib and hts-nim are implementation dependencies named in the README and paper. ### 来源 - - - - - input.source_facts.package-manager ## 安全说明 没有找到 mosdepth 的匹配本地密钥处理 manifest。Nucleus 软件包元数据仍在此发布，以便未来覆盖拥有稳定的软件包 URL。 ## 其他软件包管理器记录 - Nix - mosdepth: normalized package name match | nixpkgs package indexes: pkgs/by-name/mo/mosdepth/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1 - Ubuntu apt - mosdepth - 0.3.6+ds-1: normalized package name match | Ubuntu 24.04 LTS package indexes: mosdepth from https://archive.ubuntu.com/ubuntu/dists/noble/universe/binary-amd64/Packages.gz | BAM/CRAM depth calculation biological sequencing | https://github.com/brentp/mosdepth - Ubuntu apt - mosdepth-examples - 0.3.6+ds-1: normalized package name match | Ubuntu 24.04 LTS package indexes: mosdepth-examples from https://archive.ubuntu.com/ubuntu/dists/noble/universe/binary-amd64/Packages.gz | Test data for mosdepth | https://github.com/brentp/mosdepth ## Combined YAML source View the package source record on GitHub. [combined/mosdepth.yml](https://github.com/mxcl/pkgdb/blob/main/combined/mosdepth.yml) ## 来源 - pkg.so package database - curated package history - pkgdb category and tag curation - external package-manager database matches - cross-ecosystem install command graph