# 使用 Homebrew 安装 miniprot

查看 miniprot 的安装路径、可执行文件、元数据以及面向 AI 代理工作流的安全说明。

## 安装

```sh
sudo av install brew:miniprot
```

其他安装命令:

### macOS

- Homebrew (100%):

```sh
brew install miniprot
```

  证据: local Homebrew formula metadata

## 软件包事实

- **软件包键:** brew:miniprot
- **软件包管理器:** Homebrew
- **版本:** 0.18
- **来源摘要:** Align proteins to genomes with splicing and frameshift
- **主页:** <https://lh3.github.io/miniprot/>
- **仓库:** <https://github.com/lh3/miniprot>
- **已生成:** 2026-08-03T19:37:03+00:00

## 可执行文件

- miniprot (别名)

## 安装行为

- Bottle: 不可用

## 版本和新鲜度

- 页面生成时间: 2026-08-03
- 管理器版本: 0.18
## 项目历史与用法

miniprot is Heng Li's protein-to-genome aligner for genome annotation. The preprint appeared in 2022 and the Bioinformatics paper was published in 2023, describing miniprot as a new aligner for mapping protein sequences to complete genomes with k-mer sketching and vectorized dynamic programming.

### 项目历史

The program fills a bioinformatics gap between older tools such as GeneWise and Exonerate and the scale of modern genome projects. Its README says it aligns protein sequences against genomes with affine gap penalties, splicing, and frameshifts, primarily to annotate protein-coding genes in a new species using known genes from other species. It can build a genome index, output protein PAF, emit GFF3 with embedded PAF, and optionally use splice scores from minisplice.

### 使用方式

Adoption is source-backed through bioinformatics workflows rather than general-purpose package popularity. BUSCO's user guide lists miniprot among third-party tools to cite, and the GALBA genome-annotation pipeline paper describes genome annotation with miniprot and AUGUSTUS. Homebrew packages it as a single `miniprot` executable for the scientific-command-line niche, alongside Bioconda-style distribution and upstream source builds.

### 来源

- <https://arxiv.org/abs/2210.08052>
- <https://busco.ezlab.org/busco_userguide.html>
- <https://doi.org/10.1186/s12859-023-05449-z>
- <https://formulae.brew.sh/formula/miniprot>
- <https://github.com/lh3/miniprot>
- <https://lh3.github.io/miniprot/miniprot.html>
- <https://pubmed.ncbi.nlm.nih.gov/36648328/>


## 安全说明

narrow executable package without higher-risk signals.

- **Geiger 风险:** 绿色 / 低
- narrow executable package without higher-risk signals


## Combined YAML source

View the package source record on GitHub. [combined/miniprot.yml](https://github.com/mxcl/pkgdb/blob/main/combined/miniprot.yml)


## 来源

- pkg.so package database
- Geiger risk classifier
- curated package history
- pkgdb category and tag curation
- cross-ecosystem install command graph