# 使用 Homebrew 安装 minibwa

查看 minibwa 的安装路径、可执行文件、元数据以及面向 AI 代理工作流的安全说明。

## 安装

```sh
sudo av install brew:minibwa
```

其他安装命令:

### macOS

- Homebrew (100%):

```sh
brew install minibwa
```

  证据: local Homebrew formula metadata

## 软件包事实

- **软件包键:** brew:minibwa
- **软件包管理器:** Homebrew
- **版本:** 0.6
- **来源摘要:** Successor of BWA-MEM for short-read alignment
- **主页:** <https://github.com/lh3/minibwa>
- **仓库:** <https://github.com/lh3/minibwa>
- **最后更新:** 2026-07-30T15:48:22Z
- **已生成:** 2026-08-03T19:37:03+00:00

## 可执行文件

- minibwa (别名)

## 安装行为

- Bottle: 不可用

## 版本和新鲜度

- 页面生成时间: 2026-08-03
- 管理器版本: 0.6
## 项目历史与用法

minibwa is a genomic read aligner from the BWA/minimap2 lineage. The repository identifies it as the successor of BWA-MEM for short-read alignment, and the arXiv preprint by Heng Li and Nils Homer presents it as a next iteration of BWA-MEM for standard whole-genome short reads, Hi-C reads, accurate long reads, and directional bisulfite sequencing data.

### 项目历史

The design deliberately mixes earlier tools by the same lineage: a BWA-MEM-style BWT/FM-index and variable-length seed search, ropebwt3-inspired supermaximal exact-match work, and minimap2-style chaining plus SIMD-based base alignment. The authors report comparable accuracy with much higher speed than BWA-MEM and BWA-MEM2, while noting that exact BWA-MEM compatibility is traded for algorithmic improvement.

### 使用方式

In practice, minibwa is a bioinformatics command-line aligner for pipelines that map sequencing reads to a reference genome before variant calling, methylation analysis, or related downstream analysis. Its package-manager niche is narrow but important: it gives genomics users an installable replacement candidate for BWA-MEM where performance and support for newer read types matter more than byte-for-byte legacy output.

### 来源

- <https://arxiv.org/abs/2606.15357>
- <https://arxiv.org/html/2606.15357v1>
- <https://github.com/lh3/bwa>
- <https://github.com/lh3/minibwa>


## 安全说明

没有找到 minibwa 的匹配本地密钥处理 manifest。Nucleus 软件包元数据仍在此发布，以便未来覆盖拥有稳定的软件包 URL。



## Combined YAML source

View the package source record on GitHub. [combined/minibwa.yml](https://github.com/mxcl/pkgdb/blob/main/combined/minibwa.yml)


## 来源

- pkg.so package database
- curated package history
- pkgdb category and tag curation
- cross-ecosystem install command graph