# 使用 Homebrew, apt, Nix 安装 kalign 查看 kalign 的安装路径、可执行文件、元数据以及面向 AI 代理工作流的安全说明。 ## 安装 ```sh sudo av install brew:kalign ``` 其他安装命令: ### macOS - Homebrew (100%): ```sh brew install kalign ``` 证据: local Homebrew formula metadata ### Linux - Debian apt (92%): ```sh sudo apt install kalign ``` 证据: Debian stable package indexes: kalign from https://deb.debian.org/debian/dists/stable/main/binary-amd64/Packages.xz - Nix (92%): ```sh nix profile install nixpkgs#kalign ``` 证据: nixpkgs package indexes: pkgs/by-name/ka/kalign/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1 ## 软件包事实 - **软件包键:** brew:kalign - **软件包管理器:** Homebrew - **版本:** 3.5.1 - **来源摘要:** Fast multiple sequence alignment program for biological sequences - **主页:** - **仓库:** - **已生成:** 2026-08-03T19:37:03+00:00 ## 可执行文件 - kalign (别名) ## 安装行为 - Bottle: 不可用 ## 版本和新鲜度 - 页面生成时间: 2026-08-03 - 管理器版本: 3.5.1 ## 项目历史与用法 Kalign is a fast multiple-sequence-alignment program for protein, DNA, and RNA sequences, distributed as a command-line bioinformatics tool. ### 项目历史 Timo Lassmann and Erik Sonnhammer published the original Kalign method in BMC Bioinformatics on 2005-12-12. The paper described a Wu-Manber-based progressive alignment method intended to improve both speed and accuracy for large comparative-genomics workloads. ### 采用历史 Kalign remained in the bioinformatics toolchain because multiple sequence alignment is a routine upstream step for homology, conserved-motif, phylogeny, and structure-oriented analyses. Kalign 3, published in Bioinformatics in 2019, was presented as a complete rewrite to handle larger protein and nucleotide sequence sets, using SIMD-accelerated distance estimation and fast guide-tree construction. ### 使用方式 Users run kalign on FASTA-like biological sequence inputs to produce multiple alignments. The modern README describes progressive alignment with multi-threading support, source builds with CMake, and alternatives such as Zig builds and Python packaging. ### 为什么软件包爱好者会关心 Kalign is a classic science CLI package: a published algorithm wrapped in a small executable, useful in scripts and pipelines, with package-manager availability making a cited method reproducible without hand-building a lab-specific binary. ### 时间线 - 2005-12-12: Original Kalign paper published in BMC Bioinformatics. - 2019-10-26: Kalign 3 paper published in Bioinformatics. - 2019-10-28: GitHub release 3.1 published. - 2020-11-06: v3.3 release added multi-threading. - 2026-02-27: Kalign 3.5.1 published. ### Related projects - Related multiple-sequence-alignment tools include ClustalW, MAFFT, MUSCLE, T-Coffee, and other progressive or consistency-based MSA programs. ### 来源 - - - - ## 安全说明 narrow executable package without higher-risk signals. - **Geiger 风险:** 绿色 / 低 - narrow executable package without higher-risk signals ## 其他软件包管理器记录 - Debian apt - kalign - 1:3.4.0-1+b3: normalized package name match | Debian stable package indexes: kalign from https://deb.debian.org/debian/dists/stable/main/binary-amd64/Packages.xz | Global and progressive multiple sequence alignment | https://msa.sbc.su.se/ - Nix - kalign: normalized package name match | nixpkgs package indexes: pkgs/by-name/ka/kalign/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1 - Ubuntu apt - kalign - 1:3.3.5-1: normalized package name match | Ubuntu 24.04 LTS package indexes: kalign from https://archive.ubuntu.com/ubuntu/dists/noble/universe/binary-amd64/Packages.gz | Global and progressive multiple sequence alignment | https://msa.sbc.su.se/ ## Combined YAML source View the package source record on GitHub. [combined/kalign.yml](https://github.com/mxcl/pkgdb/blob/main/combined/kalign.yml) ## 来源 - pkg.so package database - Geiger risk classifier - curated package history - pkgdb category and tag curation - external package-manager database matches - cross-ecosystem install command graph