# 使用 Homebrew 安装 fastga

查看 fastga 的安装路径、可执行文件、元数据以及面向 AI 代理工作流的安全说明。

## 安装

```sh
sudo av install brew:fastga
```

其他安装命令:

### macOS

- Homebrew (100%):

```sh
brew install fastga
```

  证据: local Homebrew formula metadata

## 软件包事实

- **软件包键:** brew:fastga
- **软件包管理器:** Homebrew
- **版本:** 1.5
- **来源摘要:** Pairwise whole genome aligner
- **主页:** <https://github.com/thegenemyers/FASTGA>
- **仓库:** <https://github.com/thegenemyers/FASTGA>
- **最后更新:** 2026-08-02T16:35:31+09:00
- **已生成:** 2026-08-03T19:37:03+00:00

## 可执行文件

- ALNchain (别名)
- ALNplot (别名)
- ALNreset (别名)
- ALNshow (别名)
- ALNtoPAF (别名)
- ALNtoPSL (别名)
- ANOshow (别名)
- ANOstat (别名)
- ANOtoBED (别名)
- BEDtoANO (别名)
- FAtoGDB (别名)
- FastGA (别名)
- FastKS (别名)
- GDBshow (别名)
- GDBstat (别名)
- GDBtoFA (别名)
- GIXcp (别名)
- GIXmake (别名)
- GIXmv (别名)
- GIXrm (别名)
- GIXshow (别名)
- ONEalnTEST (别名)
- ONEview (别名)
- PAFtoALN (别名)
- PAFtoPSL (别名)

## 安装行为

- Bottle: 不可用

## 版本和新鲜度

- 页面生成时间: 2026-08-03
- 管理器版本: 1.5
## 项目历史与用法

FASTGA is a pairwise whole-genome aligner by Gene Myers and Chenxi Zhou. It compares two genomes, or a genome against itself, and outputs alignments in formats such as `.1aln`, PAF, and PSL.

### 项目历史

The FASTGA README identifies the authors, gives May 10, 2023 as the first date, and describes the tool as a fast genome aligner for high-quality, nearly complete genomes. Its design builds on adaptive seed finding and the wave-based local alignment approach associated with Myers' earlier DALIGNER work.

The package is more than one binary. It includes conversion, indexing, viewing, plotting, annotation, and file-management utilities around genome databases, genome indexes, ONEcode alignment files, PAF, PSL, BED, and ANO files.

The README's version notes show active development through 2025, including soft masking, log-file support for HPC cluster use, improved GIXmake memory behavior, faster conversion utilities, a ONEaln C library, and ANO annotation-file support.

### 采用历史

FASTGA is niche scientific software rather than a general developer tool, but its official README includes Bioconda and Anaconda badges and Homebrew packages it as a formula. That places it in the practical bioinformatics packaging ecosystem where command-line tools are installed into reproducible analysis environments.

Its adoption case is strongest for users who already understand genome alignment workflows and want a performant aligner with reusable intermediate genome databases and indexes. The README emphasizes comparing large genomes quickly, keeping compact binary alignment outputs, and converting to common exchange formats when needed.

### 使用方式

Basic usage can be as simple as `FastGA A B` for two FASTA or ONEcode sequence inputs, streaming PAF output by default. The tool can also compare a genome against itself, keep persistent GDB and GIX intermediates, output PSL or binary ONEcode ALN files, and convert results with helper tools such as ALNtoPAF and ALNtoPSL.

FASTGA's workflow creates or reuses genome databases and genome indexes, then records alignments in a compact `.1aln` representation. Users handling repeated comparisons can prebuild GDB and GIX files to avoid repeated conversion and indexing costs.

### 为什么软件包爱好者会关心

FASTGA is package-nerd interesting because bioinformatics packages often ship a constellation of small command-line utilities rather than one executable. The Homebrew formula exposes a whole toolkit for converting, indexing, aligning, inspecting, plotting, and translating genome alignment data.

Its significance is also in file formats: GDB, GIX, `.1aln`, ONEcode, PAF, PSL, BED, and ANO support make it useful in pipelines where compact intermediate storage and standards-adjacent interchange formats both matter.

### 时间线

- 2023: The README records May 10, 2023 as the first date for FASTGA.
- 2025: Version 1.3 added soft masking and log-file support.
- 2025: Version 1.4 added the ONEaln C library.
- 2025: Version 1.5 added ONEcode ANO-file support.

### Related projects

- DALIGNER is cited by FASTGA as an earlier Myers aligner whose wave-based local aligner influenced FASTGA.
- ONEcode is used for FASTGA's genome database and alignment encodings.
- PAF and PSL are common output formats FASTGA can emit or convert to.

### 来源

- <https://github.com/thegenemyers/FASTGA>
- <https://github.com/thegenemyers/FASTGA#readme>
- <https://github.com/thegenemyers/DALIGNER>
- <https://github.com/thegenemyers/ONEcode>


## 安全说明

narrow executable package without higher-risk signals.

- **Geiger 风险:** 绿色 / 低
- narrow executable package without higher-risk signals


## Combined YAML source

View the package source record on GitHub. [combined/fastga.yml](https://github.com/mxcl/pkgdb/blob/main/combined/fastga.yml)


## 来源

- pkg.so package database
- Geiger risk classifier
- curated package history
- pkgdb category and tag curation
- cross-ecosystem install command graph