# 使用 Homebrew 安装 miniprot

查看 miniprot 的安装路径、可执行文件、元数据以及面向 AI 代理工作流的安全说明。

## 安装

```sh
sudo av install brew:miniprot
```

其他安装命令:

### macOS

- Homebrew (100%):

```sh
brew install miniprot
```

  证据: local Homebrew formula metadata

## 软件包事实

- **软件包键:** brew:miniprot
- **软件包管理器:** Homebrew
- **软件包管理器页面:** <https://formulae.brew.sh/formula/miniprot>
- **版本:** 0.18
- **来源摘要:** Align proteins to genomes with splicing and frameshift
- **主页:** <https://lh3.github.io/miniprot/>
- **仓库:** <https://github.com/lh3/miniprot>
- **上游文档:** <https://lh3.github.io/miniprot/>
- **许可证:** MIT
- **源码归档:** <https://github.com/lh3/miniprot/archive/refs/tags/v0.18.tar.gz>
- **已生成:** 2026-08-04T22:13:35+00:00

## 可执行文件

- miniprot (cli)
- miniprot (别名)

## 安装行为

- post-install 钩子: 未定义
- Bottle: 可用 于 arm64_linux, arm64_sequoia, arm64_sonoma, arm64_tahoe, sonoma, x86_64_linux

## 版本和新鲜度

- 页面生成时间: 2026-08-04
- 管理器版本: 0.18
- 本地数据: OK
- 上游仓库: https://github.com/lh3/miniprot
- 检测到的最新版本: v0.18 (当前)
- 信息: No package-manager update timestamp was available.
## 项目历史与用法

miniprot is Heng Li's protein-to-genome aligner for genome annotation. The preprint appeared in 2022 and the Bioinformatics paper was published in 2023, describing miniprot as a new aligner for mapping protein sequences to complete genomes with k-mer sketching and vectorized dynamic programming.

### 项目历史

The program fills a bioinformatics gap between older tools such as GeneWise and Exonerate and the scale of modern genome projects. Its README says it aligns protein sequences against genomes with affine gap penalties, splicing, and frameshifts, primarily to annotate protein-coding genes in a new species using known genes from other species. It can build a genome index, output protein PAF, emit GFF3 with embedded PAF, and optionally use splice scores from minisplice.

### 使用方式

Adoption is source-backed through bioinformatics workflows rather than general-purpose package popularity. BUSCO's user guide lists miniprot among third-party tools to cite, and the GALBA genome-annotation pipeline paper describes genome annotation with miniprot and AUGUSTUS. Homebrew packages it as a single `miniprot` executable for the scientific-command-line niche, alongside Bioconda-style distribution and upstream source builds.

### 来源

- <https://arxiv.org/abs/2210.08052>
- <https://busco.ezlab.org/busco_userguide.html>
- <https://doi.org/10.1186/s12859-023-05449-z>
- <https://formulae.brew.sh/formula/miniprot>
- <https://github.com/lh3/miniprot>
- <https://lh3.github.io/miniprot/miniprot.html>
- <https://pubmed.ncbi.nlm.nih.gov/36648328/>


## 安全说明

narrow executable package without higher-risk signals.

- **Geiger 风险:** 绿色 / 低
- narrow executable package without higher-risk signals

## 源数据库详情

- **Source Database:** Homebrew formula API
- **Tap:** homebrew/core
- **Full Name:** miniprot
- **Version Scheme:** 0
- **Revision:** 0
- **Bottle Stable Root URL:** <https://ghcr.io/v2/homebrew/core>
- **Deprecated:** no
- **Disabled:** no
- **Keg Only:** no
- **URL Keys:** stable


## 相关链接

- [Source-control packages](https://pkg.so/zh-hans/source-control-tools/) - Belongs to a source-control command family.
- [Terminal utility packages](https://pkg.so/zh-hans/terminal-utilities/) - Matched terminal and command-line workflow metadata.
- [Networking and protocol packages](https://pkg.so/zh-hans/networking-protocol-tools/) - Matched network, protocol, or remote-service metadata.
- [Scientific computing packages](https://pkg.so/zh-hans/scientific-computing-tools/) - Matched scientific computing metadata.
- [samtools](https://pkg.so/zh-hans/brew/samtools/) - Shares pkgdb curated category or tags: bioinformatics, cli, genomics, science.
- [blast](https://pkg.so/zh-hans/brew/blast/) - Shares pkgdb curated category or tags: bioinformatics, cli, genomics, science.
- [bedtools](https://pkg.so/zh-hans/brew/bedtools/) - Shares pkgdb curated category or tags: bioinformatics, cli, genomics, science.
- [minimap2](https://pkg.so/zh-hans/brew/minimap2/) - Shares pkgdb curated category or tags: bioinformatics, cli, genomics, science.
- [bbtools](https://pkg.so/zh-hans/brew/bbtools/) - Shares pkgdb curated category or tags: bioinformatics, cli, genomics, science.
- [sambamba](https://pkg.so/zh-hans/brew/sambamba/) - Shares pkgdb curated category or tags: bioinformatics, cli, genomics, science.
- [abricate](https://pkg.so/zh-hans/brew/abricate/) - Shares pkgdb curated category or tags: bioinformatics, cli, genomics, science.
- [picard-tools](https://pkg.so/zh-hans/brew/picard-tools/) - Shares pkgdb curated category or tags: bioinformatics, cli, genomics, science.
- [minigraph](https://pkg.so/zh-hans/brew/minigraph/) - Local package facts share a topical domain. Shared terms: bioinformatics, cli, genomics, mapping, science.
- [mummer](https://pkg.so/zh-hans/brew/mummer/) - Local package facts share a topical domain. Shared terms: alignment, bioinformatics, cli, genomics, protein.

## Combined YAML source

View the package source record on GitHub. [combined/miniprot.yml](https://github.com/mxcl/pkgdb/blob/main/combined/miniprot.yml)


## 来源

- pkg.so package database
- Geiger risk classifier
- package-page enrichment
- curated package history
- package version freshness
- pkgdb category and tag curation
- package relationship graph
- cross-ecosystem install command graph
