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Install rasusa with Homebrew

Randomly subsample sequencing reads or alignments. Version 5.1.0 via Homebrew; verified 2026-09-13.

Install commandSecurity notes

install

Additional install commands

macOS

Homebrewverified · 100%
brew install rasusa

local Homebrew formula metadata

overview

Package summary

Randomly subsample sequencing reads or alignments

Commands and aliases

  • rasusa

history

Project history and usage

Rasusa is a Rust command-line program for randomly downsampling sequencing reads or genome alignments, including targeting a requested sequencing coverage.

Project history

Rasusa was created to randomly subsample sequencing reads to a requested coverage. Its methods and purpose were documented in a 2022 Journal of Open Source Software paper. The project subsequently expanded beyond FASTQ reads to support unaligned and aligned SAM, BAM, and CRAM workflows, with alignment downsampling documented in a 2026 Gigabyte paper.

Adoption history

Rasusa is available through precompiled release binaries, Cargo and cargo-binstall, Bioconda, containers, and Homebrew. The official README documents the shift of container distribution from Docker Hub to Quay.io and later to GitHub Container Registry.

How it is used

For reads, users supply FASTQ or unaligned SAM/BAM/CRAM input and request a coverage or other sampling target; results are written to standard output unless otherwise directed. Current releases also provide alignment-oriented downsampling. The CLI supports paired sequencing data and integrates readily into shell and bioinformatics pipelines.

Why package nerds care

Rasusa packages a common bioinformatics preprocessing task into a fast, reproducible Rust executable with few operational complications. Its presence across Cargo, Bioconda, containers, and Homebrew illustrates how research software can bridge language-native, scientific-workflow, and general-purpose package ecosystems.

Timeline

  • 2022: Rasusa was described in the Journal of Open Source Software.
  • Before 0.4.0: Official containers were hosted on Docker Hub.
  • 0.4.0–2.2.0: Official containers were hosted on Quay.io.
  • 2026: Efficient genome-alignment downsampling with Rasusa was described in Gigabyte.

Related projects

  • Cargo and cargo-binstall distribute the Rust executable.
  • Bioconda integrates Rasusa into bioinformatics package and workflow environments.
  • SAM, BAM, CRAM, and FASTQ are the principal sequencing formats handled by the tool.

security posture

Risk level: green

narrow executable package without higher-risk signals.

Risk classifier

green risk · low confidence · appliance

Why

  • narrow executable package without higher-risk signals

Signals

  • metadata:no-higher-risk-signals

Install behavior

  • No Homebrew post-install hook is recorded in formula metadata.
  • Homebrew bottle metadata is available for 6 platform targets.
  • Build metadata lists 1 build dependencies.

Recommended review

Before unattended agent use, check whether the tool reads plaintext credentials, writes remote state, publishes artifacts, or shells out to plugins.

executables

Installed executables

CommandKindExposureNote
rasusacliglobal executable

freshness

Version and freshness

These signals separate page generation age, package-manager activity, and upstream release comparison. Version lag is warned only when an evidence URL and comparable versions are present.

page generated2026-09-19
manager version5.1.0
manager updated2026-09-13
local dataok
upstreamcurrent
latest detected5.1.0

https://github.com/mbhall88/rasusa

  • okNo freshness warnings were generated.

install metadata

Package metadata

Package keybrew:rasusa
Version5.1.0
Package managerHomebrew
Package manager pagehttps://formulae.brew.sh/formula/rasusa
Homepagehttps://doi.org/10.21105/joss.03941
Repositoryhttps://github.com/mbhall88/rasusa
Upstream docshttps://doi.org/10.21105/joss.03941
LicenseMIT
Source archivehttps://github.com/mbhall88/rasusa/archive/refs/tags/5.1.0.tar.gz
Last updated2026-09-13T07:18:51Z
Pulseupdated
Build dependenciesrust
Bottleavailable (on arm64_linux, arm64_sequoia, arm64_sonoma, arm64_tahoe, sonoma, x86_64_linux)
Homebrew post-installnot defined
Servicenone declared

registry facts

Source database details

Source DatabaseHomebrew formula API
Taphomebrew/core
Full Namerasusa
Version Scheme0
Revision0
Head VersionHEAD
Bottle Stable Root URLhttps://ghcr.io/v2/homebrew/core
Deprecatedno
Disabledno
Keg Onlyno
URL Keys
  • head
  • stable

package graph

Links come from deterministic package relationships, av.db category and tag curation, ecosystem matches, and package hub membership.

Related tools

  • rustBuild dependency declared by Homebrew.

Same workflow

  • fastpShares pkgdb curated category or tags: bioinformatics, cli, fastq, science, sequencing.
  • trim-galoreShares pkgdb curated category or tags: bioinformatics, cli, fastq, science, sequencing.
  • fastq-toolsShares pkgdb curated category or tags: bioinformatics, cli, fastq, science, sequencing.
  • badreadShares pkgdb curated category or tags: bioinformatics, cli, science, sequencing.
  • fastqcShares pkgdb curated category or tags: bioinformatics, cli, fastq, science, sequencing.
  • adapterremovalShares pkgdb curated category or tags: bioinformatics, cli, fastq, science, sequencing.

source trail

Generated from repository data

This page is generated by av-web from the private package SQLite artifact built by scripts/generate-pkg-sqlite.py.

Used sources

  • Geiger risk classifier
  • cross-ecosystem install command graph
  • curated package history
  • package relationship graph
  • package version freshness
  • package-page enrichment
  • pkg.so package database
  • pkgdb category and tag curation