macOS
brew install fastanilocal Homebrew formula metadata
brew / rank 11303
Fast whole-genome similarity (ANI) estimation. Version 1.34 via Homebrew; verified 2026-07-25. Also installable with debian: sudo apt install fastani.
install
brew install fastanilocal Homebrew formula metadata
sudo apt install fastaniDebian stable package indexes · fastani · source: deb.debian.org
overview
Fast whole-genome similarity (ANI) estimation
history
FastANI is a command-line bioinformatics tool for rapidly estimating average nucleotide identity between complete or draft microbial genomes. It replaces expensive all-against-all alignments with approximate sequence mapping, making ANI practical for large genome collections.
The official FastANI repository was created in 2017. FastANI uses Mashmap as a MinHash-based sequence mapping engine and follows the broad workflow of earlier ANI methods while avoiding their expensive sequence-alignment step.
The associated 2018 Nature Communications paper introduced FastANI as a scalable ANI method and used it to analyze more than 90,000 prokaryotic genomes. The study reported accuracy comparable to alignment-based ANI methods in the intended similarity range with speedups of two to three orders of magnitude.
FastANI became a practical command-line component in microbial genomics because it accepts both complete and draft assemblies and supports one-to-one, one-to-many, and many-to-many comparisons. The supplied package metadata shows distribution through Homebrew, Debian, and Ubuntu, complementing upstream source builds and release binaries.
Users provide a query genome and reference genome, or text files listing multiple query and reference assemblies. FastANI writes tab-delimited ANI results and can optionally generate a lower-triangular PHYLIP-style matrix.
The official README recommends checking assembly quality and notes that pairs far below roughly 80 percent ANI are outside FastANI's useful nucleotide-level range. It also documents multi-threading and a small query/reference asymmetry in pairwise estimates.
FastANI matters to package users because it turns a computationally expensive comparative-genomics method into a scriptable executable suitable for large batches. Its small CLI surface, release binaries, and Linux and macOS package availability make it easy to place inside reproducible genome-classification pipelines.
security posture
No matching local secret-handling manifest was found for fastani. Nucleus package metadata is still published here so future coverage has a stable package URL.
Before unattended agent use, check whether the tool reads plaintext credentials, writes remote state, publishes artifacts, or shells out to plugins.
executables
| Command | Kind | Exposure | Note |
|---|---|---|---|
fastANI | executable | indexed executable | Discovered from the local executable index. |
freshness
These signals separate page generation age, package-manager activity, and upstream release comparison. Version lag is warned only when an evidence URL and comparable versions are present.
install metadata
| Package key | brew:fastani |
|---|---|
| Version | 1.34 |
| Package manager | Homebrew |
| Homepage | https://github.com/ParBLiSS/FastANI |
| Repository | https://github.com/ParBLiSS/FastANI |
| Last updated | 2026-07-25T01:07:37Z |
| Pulse | updated |
| Bottle | not recorded |
| Service | none declared |
source database matches
Matches are pulled from external package-manager indexes and kept separate from local Automic Vault package links.
fastani 1.33-3+b1
Fast alignment-free computation of whole-genome Average Nucleotide Identity
https://github.com/ParBLiSS/FastANI
sudo apt install fastanifastani 1.33-3
Fast alignment-free computation of whole-genome Average Nucleotide Identity
https://github.com/ParBLiSS/FastANI
sudo apt install fastanisource trail
This page is generated by av-web from the private package SQLite artifact built by scripts/generate-pkg-sqlite.py.
View the package source record on GitHub.