# Install diamond with Homebrew, Nix

Accelerated BLAST compatible local sequence aligner. Version 2.2.4 via Homebrew; verified 2026-07-13. Also installable with nix: nix profile install nixpkgs#diamond.

## Install

```sh
sudo av install brew:diamond
```

Additional install commands:

### macOS

- Homebrew (100%):

```sh
brew install diamond
```

  Evidence: local Homebrew formula metadata

### Linux

- Nix (92%):

```sh
nix profile install nixpkgs#diamond
```

  Evidence: nixpkgs package indexes: pkgs/by-name/di/diamond/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1

## Package facts

- **Package key:** brew:diamond
- **Package manager:** Homebrew
- **Version:** 2.2.4
- **Source summary:** Accelerated BLAST compatible local sequence aligner
- **Homepage:** <https://github.com/bbuchfink/diamond>
- **Repository:** <https://github.com/bbuchfink/diamond>
- **Last updated:** 2026-07-13T15:30:35Z
- **Generated:** 2026-08-03T19:37:03+00:00

## Executables

- diamond (alias)

## Install behavior

- Bottle: not available

## Freshness

- Page generated: 2026-08-03
- Package-manager version: 2.2.4
## Project history and usage

DIAMOND is a high-performance sequence aligner for protein and translated DNA searches, positioned as a BLAST-compatible tool for large biological datasets.

### Project history

The README says the initial version was developed by Benjamin J. Buchfink at the Huson lab, University of Tuebingen, from 2013 to 2015. Later development continued independently, with support from an EXIST grant in 2018-2019 and the Max Planck Institute for Biology Tuebingen from 2019 to 2024.

### Adoption history

DIAMOND's adoption is tied to its promise of much faster BLAST-like protein and translated DNA alignment. The README highlights 100x to 10,000x BLAST speed, low resource requirements, downloads from GitHub releases, Bioconda availability, Galaxy integration, and citation badges.

### How it is used

Package users install DIAMOND when they need command-line database creation, protein search, translated DNA search, sequence clustering, taxonomic classification, or BLAST-style tabular, pairwise, and XML outputs.

### Why package nerds care

DIAMOND is significant because it is a research-grade bioinformatics workhorse that also behaves like a normal packaged CLI. That combination makes it common in reproducible pipelines, containers, Conda environments, Homebrew installs, and HPC workflows.

### Timeline

- 2013-2015: Initial version developed at the Huson lab, University of Tuebingen.
- 2015: Original DIAMOND publication cited in the README.
- 2021: Sensitive protein alignments at tree-of-life scale publication cited in the README.
- 2026: v2.2.2 release published on GitHub.

### Related projects

- The README frames DIAMOND as BLAST-compatible and links it to Bioconda and the European Galaxy server for workflow use.

### Sources

- <https://github.com/bbuchfink/diamond>
- <https://raw.githubusercontent.com/bbuchfink/diamond/master/README.md>
- <https://api.github.com/repos/bbuchfink/diamond>
- <https://github.com/bbuchfink/diamond/releases/tag/v2.2.2>


## Security Notes

No matching local secret-handling manifest was found for diamond. Nucleus package metadata is still published here so future coverage has a stable package URL.


## Other Package-Manager Records

- Nix - diamond: normalized package name match | nixpkgs package indexes: pkgs/by-name/di/diamond/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1


## Combined YAML source

View the package source record on GitHub. [combined/diamond.yml](https://github.com/mxcl/pkgdb/blob/main/combined/diamond.yml)


## Sources

- pkg.so package database
- Geiger risk classifier
- curated package history
- pkgdb category and tag curation
- external package-manager database matches
- cross-ecosystem install command graph