# miniprot を Homebrew でインストール

miniprot のインストール経路、実行ファイル、メタデータ、AI エージェント向けセキュリティノートを確認します。

## インストール

```sh
sudo av install brew:miniprot
```

追加のインストールコマンド:

### macOS

- Homebrew (100%):

```sh
brew install miniprot
```

  証拠: local Homebrew formula metadata

## パッケージ情報

- **パッケージキー:** brew:miniprot
- **パッケージマネージャ:** Homebrew
- **バージョン:** 0.18
- **ソース概要:** Align proteins to genomes with splicing and frameshift
- **ホームページ:** <https://lh3.github.io/miniprot/>
- **リポジトリ:** <https://github.com/lh3/miniprot>
- **生成日時:** 2026-08-03T19:37:03+00:00

## 実行可能ファイル

- miniprot (エイリアス)

## インストール挙動

- Bottle: 利用不可

## バージョンと鮮度

- ページ生成日: 2026-08-03
- マネージャ版: 0.18
## プロジェクトの歴史と使われ方

miniprot is Heng Li's protein-to-genome aligner for genome annotation. The preprint appeared in 2022 and the Bioinformatics paper was published in 2023, describing miniprot as a new aligner for mapping protein sequences to complete genomes with k-mer sketching and vectorized dynamic programming.

### プロジェクトの歴史

The program fills a bioinformatics gap between older tools such as GeneWise and Exonerate and the scale of modern genome projects. Its README says it aligns protein sequences against genomes with affine gap penalties, splicing, and frameshifts, primarily to annotate protein-coding genes in a new species using known genes from other species. It can build a genome index, output protein PAF, emit GFF3 with embedded PAF, and optionally use splice scores from minisplice.

### 使われ方

Adoption is source-backed through bioinformatics workflows rather than general-purpose package popularity. BUSCO's user guide lists miniprot among third-party tools to cite, and the GALBA genome-annotation pipeline paper describes genome annotation with miniprot and AUGUSTUS. Homebrew packages it as a single `miniprot` executable for the scientific-command-line niche, alongside Bioconda-style distribution and upstream source builds.

### ソース

- <https://arxiv.org/abs/2210.08052>
- <https://busco.ezlab.org/busco_userguide.html>
- <https://doi.org/10.1186/s12859-023-05449-z>
- <https://formulae.brew.sh/formula/miniprot>
- <https://github.com/lh3/miniprot>
- <https://lh3.github.io/miniprot/miniprot.html>
- <https://pubmed.ncbi.nlm.nih.gov/36648328/>


## セキュリティノート

narrow executable package without higher-risk signals.

- **Geiger リスク:** グリーン / 低
- narrow executable package without higher-risk signals


## Combined YAML source

View the package source record on GitHub. [combined/miniprot.yml](https://github.com/mxcl/pkgdb/blob/main/combined/miniprot.yml)


## ソース

- pkg.so package database
- Geiger risk classifier
- curated package history
- pkgdb category and tag curation
- cross-ecosystem install command graph