# blast を Homebrew, Nix でインストール
blast のインストール経路、実行ファイル、メタデータ、AI エージェント向けセキュリティノートを確認します。
## インストール
```sh
sudo av install brew:blast
```
追加のインストールコマンド:
### macOS
- Homebrew (100%):
```sh
brew install blast
```
証拠: local Homebrew formula metadata
### Linux
- Nix (92%):
```sh
nix profile install nixpkgs#blast
```
証拠: nixpkgs package indexes: pkgs/by-name/bl/blast/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1
## パッケージ情報
- **パッケージキー:** brew:blast
- **パッケージマネージャ:** Homebrew
- **バージョン:** 2.17.0
- **ソース概要:** Basic Local Alignment Search Tool
- **ホームページ:**
- **最終更新:** 2026-06-22T14:02:53-07:00
- **生成日時:** 2026-08-03T19:37:03+00:00
## 実行可能ファイル
- blast_formatter (エイリアス)
- blastdb_aliastool (エイリアス)
- blastdb_convert (エイリアス)
- blastdb_path (エイリアス)
- blastdbcheck (エイリアス)
- blastdbcmd (エイリアス)
- blastdbcp (エイリアス)
- blastn (エイリアス)
- blastp (エイリアス)
- blastx (エイリアス)
- cleanup-blastdb-volumes.py (エイリアス)
- convert2blastmask (エイリアス)
- datatool (エイリアス)
- deltablast (エイリアス)
- dustmasker (エイリアス)
- gc_cli (エイリアス)
- get_species_taxids.sh (エイリアス)
- legacy_blast.pl (エイリアス)
- lmdbxx_sample (エイリアス)
- makeblastdb (エイリアス)
- makeclusterdb (エイリアス)
- makembindex (エイリアス)
- makeprofiledb (エイリアス)
- project_tree_builder (エイリアス)
- psiblast (エイリアス)
- rpsblast (エイリアス)
- rpstblastn (エイリアス)
- run_with_lock (エイリアス)
- seedtop (エイリアス)
- segmasker (エイリアス)
- seqdb_demo (エイリアス)
- seqdb_perf (エイリアス)
- tax4blast (エイリアス)
- tblastn (エイリアス)
- tblastx (エイリアス)
- update_blastdb.pl (エイリアス)
- windowmasker (エイリアス)
- windowmasker_2.2.22_adapter.py (エイリアス)
## インストール挙動
- Bottle: 利用不可
## バージョンと鮮度
- ページ生成日: 2026-08-03
- マネージャ版: 2.17.0
## プロジェクトの歴史と使われ方
BLAST, the Basic Local Alignment Search Tool, is one of the defining command-line programs of computational biology. It became the everyday sequence-search utility for comparing DNA and protein sequences against large databases, first through NCBI services and then through local command-line installations.
### プロジェクトの歴史
NCBI's BLAST help references the 1990 Altschul, Gish, Miller, Myers, and Lipman paper that introduced the Basic Local Alignment Search Tool. The same NCBI reference list traces later BLAST-family milestones including gapped BLAST and PSI-BLAST in 1997, MegaBLAST indexing work in 2008, BLAST+ architecture in 2008, DELTA-BLAST in 2012, Magic-BLAST in 2019, and ElasticBLAST in 2023.
The command-line package distributed today is BLAST+, documented by NCBI's BLAST Command Line Applications User Manual. The developer information page identifies BLAST as public-domain software and points developers to the NCBI C++ Toolkit implementation, matching the public GitHub toolkit repository used for source distribution.
### 採用の歴史
BLAST became a standard because it joined a fast heuristic alignment algorithm with NCBI's growing public sequence databases. Web BLAST made ad hoc searches accessible, while the command-line applications let labs, sequencing centers, and pipelines run repeatable local searches against custom databases.
Package-manager adoption reflects that role: even when the upstream distribution is from NCBI rather than a typical single-purpose GitHub project, package managers keep `blastn`, `blastp`, `blastx`, `makeblastdb`, `blastdbcmd`, and related executables available as system tools for bioinformatics workflows.
### 使われ方
Common local workflows build a database with `makeblastdb`, search it with tools such as `blastn` or `blastp`, inspect databases with `blastdbcmd`, and format results with `blast_formatter`. NCBI also documents REST access for programmatic searches against hosted services.
The package contains a family of executables rather than one command. That matters for reproducible science because database construction, masking, protein-vs-nucleotide search modes, profile searches, and output formatting are split into scriptable tools.
### パッケージ好きにとっての重要性
For package nerds, BLAST is a canonical example of scientific infrastructure as a Unix package: many binaries, public-domain licensing, local database files, environment/config conventions, and a manual that is closer to laboratory protocol than app documentation.
It is also a reminder that the most important command-line tools are not always developer tools. BLAST made local compute a practical front end to public biological databases, so packaging it well directly affected how biology labs automated sequence analysis.
### タイムライン
- 1990: Original BLAST paper published.
- 1997: Gapped BLAST and PSI-BLAST paper published.
- 2008: NCBI BLAST Command Line Applications User Manual citation date and BLAST+ architecture paper appear.
- 2012: DELTA-BLAST paper published.
- 2019: Magic-BLAST paper published.
- 2023: ElasticBLAST cloud-search paper published.
### Related projects
- Related projects and descendants include PSI-BLAST, MegaBLAST, DELTA-BLAST, Magic-BLAST, ElasticBLAST, the NCBI C++ Toolkit, FASTA-family sequence search tools, and downstream workflow systems that wrap BLAST searches.
### ソース
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## セキュリティノート
infrastructure mutation or orchestration signal.
- **Geiger リスク:** orange / 中
- infrastructure mutation or orchestration signal
## Configuration and credential file locations
These source-backed paths show where this package keeps local settings or durable credentials. Automic Vault can use them as review targets for secret scanning, migration, and command approval.
## Configuration files
- Unix: .ncbirc, ~/.ncbirc, $NCBI/.ncbirc, /etc/.ncbirc
- Windows: ncbi.ini, %USERPROFILE%\ncbi.ini, %NCBI%\ncbi.ini, %SYSTEMROOT%\ncbi.ini
## 他のパッケージマネージャ記録
- Nix - blast: normalized package name match | nixpkgs package indexes: pkgs/by-name/bl/blast/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1
## Combined YAML source
View the package source record on GitHub. [combined/blast.yml](https://github.com/mxcl/pkgdb/blob/main/combined/blast.yml)
## ソース
- pkg.so package database
- Geiger risk classifier
- curated configuration and credential file locations
- curated package history
- pkgdb category and tag curation
- external package-manager database matches
- cross-ecosystem install command graph