# Installer miniprot avec Homebrew

Consultez les chemins d'installation, exécutables, métadonnées et notes de sécurité de miniprot pour les workflows d'agents IA.

## installation

```sh
sudo av install brew:miniprot
```

Commandes d'installation supplémentaires:

### macOS

- Homebrew (100%):

```sh
brew install miniprot
```

  Preuve: local Homebrew formula metadata

## Faits du paquet

- **Clé du paquet:** brew:miniprot
- **Gestionnaire de paquets:** Homebrew
- **Version:** 0.18
- **Résumé source:** Align proteins to genomes with splicing and frameshift
- **Page d'accueil:** <https://lh3.github.io/miniprot/>
- **Dépôt:** <https://github.com/lh3/miniprot>
- **Généré:** 2026-08-03T19:37:03+00:00

## exécutables

- miniprot (alias)

## Comportement d'installation

- Bouteille: non disponible

## Version et fraîcheur

- page générée: 2026-08-03
- version du gestionnaire: 0.18
## Historique du projet et usages

miniprot is Heng Li's protein-to-genome aligner for genome annotation. The preprint appeared in 2022 and the Bioinformatics paper was published in 2023, describing miniprot as a new aligner for mapping protein sequences to complete genomes with k-mer sketching and vectorized dynamic programming.

### Historique du projet

The program fills a bioinformatics gap between older tools such as GeneWise and Exonerate and the scale of modern genome projects. Its README says it aligns protein sequences against genomes with affine gap penalties, splicing, and frameshifts, primarily to annotate protein-coding genes in a new species using known genes from other species. It can build a genome index, output protein PAF, emit GFF3 with embedded PAF, and optionally use splice scores from minisplice.

### Modes d'utilisation

Adoption is source-backed through bioinformatics workflows rather than general-purpose package popularity. BUSCO's user guide lists miniprot among third-party tools to cite, and the GALBA genome-annotation pipeline paper describes genome annotation with miniprot and AUGUSTUS. Homebrew packages it as a single `miniprot` executable for the scientific-command-line niche, alongside Bioconda-style distribution and upstream source builds.

### Sources

- <https://arxiv.org/abs/2210.08052>
- <https://busco.ezlab.org/busco_userguide.html>
- <https://doi.org/10.1186/s12859-023-05449-z>
- <https://formulae.brew.sh/formula/miniprot>
- <https://github.com/lh3/miniprot>
- <https://lh3.github.io/miniprot/miniprot.html>
- <https://pubmed.ncbi.nlm.nih.gov/36648328/>


## Notes de sécurité

narrow executable package without higher-risk signals.

- **Risque Geiger:** vert / faible
- narrow executable package without higher-risk signals


## Combined YAML source

View the package source record on GitHub. [combined/miniprot.yml](https://github.com/mxcl/pkgdb/blob/main/combined/miniprot.yml)


## Sources

- pkg.so package database
- Geiger risk classifier
- curated package history
- pkgdb category and tag curation
- cross-ecosystem install command graph
