# Installer kalign avec Homebrew, apt, Nix

Consultez les chemins d'installation, exécutables, métadonnées et notes de sécurité de kalign pour les workflows d'agents IA.

## installation

```sh
sudo av install brew:kalign
```

Commandes d'installation supplémentaires:

### macOS

- Homebrew (100%):

```sh
brew install kalign
```

  Preuve: local Homebrew formula metadata

### Linux

- Debian apt (92%):

```sh
sudo apt install kalign
```

  Preuve: Debian stable package indexes: kalign from https://deb.debian.org/debian/dists/stable/main/binary-amd64/Packages.xz

- Nix (92%):

```sh
nix profile install nixpkgs#kalign
```

  Preuve: nixpkgs package indexes: pkgs/by-name/ka/kalign/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1

## Faits du paquet

- **Clé du paquet:** brew:kalign
- **Gestionnaire de paquets:** Homebrew
- **Version:** 3.5.1
- **Résumé source:** Fast multiple sequence alignment program for biological sequences
- **Page d'accueil:** <https://github.com/TimoLassmann/kalign>
- **Dépôt:** <https://github.com/TimoLassmann/kalign>
- **Généré:** 2026-08-03T19:37:03+00:00

## exécutables

- kalign (alias)

## Comportement d'installation

- Bouteille: non disponible

## Version et fraîcheur

- page générée: 2026-08-03
- version du gestionnaire: 3.5.1
## Historique du projet et usages

Kalign is a fast multiple-sequence-alignment program for protein, DNA, and RNA sequences, distributed as a command-line bioinformatics tool.

### Historique du projet

Timo Lassmann and Erik Sonnhammer published the original Kalign method in BMC Bioinformatics on 2005-12-12. The paper described a Wu-Manber-based progressive alignment method intended to improve both speed and accuracy for large comparative-genomics workloads.

### Historique d'adoption

Kalign remained in the bioinformatics toolchain because multiple sequence alignment is a routine upstream step for homology, conserved-motif, phylogeny, and structure-oriented analyses. Kalign 3, published in Bioinformatics in 2019, was presented as a complete rewrite to handle larger protein and nucleotide sequence sets, using SIMD-accelerated distance estimation and fast guide-tree construction.

### Modes d'utilisation

Users run kalign on FASTA-like biological sequence inputs to produce multiple alignments. The modern README describes progressive alignment with multi-threading support, source builds with CMake, and alternatives such as Zig builds and Python packaging.

### Pourquoi les passionnés de paquets s'y intéressent

Kalign is a classic science CLI package: a published algorithm wrapped in a small executable, useful in scripts and pipelines, with package-manager availability making a cited method reproducible without hand-building a lab-specific binary.

### Chronologie

- 2005-12-12: Original Kalign paper published in BMC Bioinformatics.
- 2019-10-26: Kalign 3 paper published in Bioinformatics.
- 2019-10-28: GitHub release 3.1 published.
- 2020-11-06: v3.3 release added multi-threading.
- 2026-02-27: Kalign 3.5.1 published.

### Related projects

- Related multiple-sequence-alignment tools include ClustalW, MAFFT, MUSCLE, T-Coffee, and other progressive or consistency-based MSA programs.

### Sources

- <https://academic.oup.com/bioinformatics/article/36/6/1928/5607735>
- <https://api.github.com/repos/TimoLassmann/kalign/releases?per_page=100>
- <https://github.com/TimoLassmann/kalign>
- <https://link.springer.com/article/10.1186/1471-2105-6-298>


## Notes de sécurité

narrow executable package without higher-risk signals.

- **Risque Geiger:** vert / faible
- narrow executable package without higher-risk signals

## Autres enregistrements de gestionnaires de paquets

- Debian apt - kalign - 1:3.4.0-1+b3: normalized package name match | Debian stable package indexes: kalign from https://deb.debian.org/debian/dists/stable/main/binary-amd64/Packages.xz | Global and progressive multiple sequence alignment | https://msa.sbc.su.se/
- Nix - kalign: normalized package name match | nixpkgs package indexes: pkgs/by-name/ka/kalign/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1
- Ubuntu apt - kalign - 1:3.3.5-1: normalized package name match | Ubuntu 24.04 LTS package indexes: kalign from https://archive.ubuntu.com/ubuntu/dists/noble/universe/binary-amd64/Packages.gz | Global and progressive multiple sequence alignment | https://msa.sbc.su.se/


## Combined YAML source

View the package source record on GitHub. [combined/kalign.yml](https://github.com/mxcl/pkgdb/blob/main/combined/kalign.yml)


## Sources

- pkg.so package database
- Geiger risk classifier
- curated package history
- pkgdb category and tag curation
- external package-manager database matches
- cross-ecosystem install command graph