# trim-galore mit Homebrew, apt installieren Prüfe Installationswege, Executables, Metadaten und Sicherheitshinweise für trim-galore in AI-Agent-Workflows. ## Installation ```sh sudo av install brew:trim-galore ``` Weitere Installationsbefehle: ### macOS - Homebrew (100%): ```sh brew install trim-galore ``` Evidenz: local Homebrew formula metadata ### Linux - Debian apt (92%): ```sh sudo apt install trim-galore ``` Evidenz: Debian stable package indexes: trim-galore from https://deb.debian.org/debian/dists/stable/main/binary-amd64/Packages.xz ## Paketfakten - **Paketschlüssel:** brew:trim-galore - **Paketmanager:** Homebrew - **Version:** 2.3.0 - **Quellzusammenfassung:** Quality and adapter trimming for FastQ sequencing reads - **Homepage:** - **Repository:** - **Zuletzt aktualisiert:** 2026-07-11T13:10:09+02:00 - **Generiert:** 2026-08-03T19:37:03+00:00 ## Executables - trim_galore (Alias) ## Installationsverhalten - Bottle: nicht verfügbar ## Version und Aktualität - Seite generiert: 2026-08-03 - Manager-Version: 2.3.0 ## Projektgeschichte und Nutzung Trim Galore is a command-line tool for adapter and quality trimming of FASTQ sequencing reads, with extra support for bisulfite and RRBS workflows. It began as a Perl wrapper around Cutadapt and FastQC and later moved to a Rust implementation that preserves the established command-line interface and output conventions. ### Projektgeschichte The original Trim Galore project was developed at Babraham Bioinformatics by Felix Krueger. Official Babraham documentation describes it as a wrapper around Cutadapt and FastQC for consistent quality and adapter trimming of FastQ files, including special handling for MspI-digested RRBS libraries. The official Trim Galore documentation describes v2.x as a faithful Rust rewrite of the earlier v0.6.x Perl tool. The rewrite consolidated adapter trimming, gzip handling, and FastQC-compatible reporting into a single static binary while retaining compatibility with common v0.6.x scripts and pipelines. ### Adoptionsgeschichte Trim Galore became common in next-generation sequencing preprocessing because it wrapped the separate Cutadapt and FastQC steps behind one stable CLI and produced conventional FASTQ outputs plus trimming reports. The current docs describe more than ten years of production use and identify the older Perl wrapper as a de-facto standard in many bisulfite sequencing pipelines. Package-manager adoption spans bioinformatics and general Unix packaging channels: the supplied package facts list Homebrew, Debian, and Ubuntu package names, while the official installation guide documents Bioconda, crates.io, Docker, source builds, and prebuilt binaries as current installation paths. ### Wie es verwendet wird Typical usage is file-oriented and pipeline-friendly: run `trim_galore input.fastq.gz` for single-end reads, `trim_galore --paired sample_R1.fastq.gz sample_R2.fastq.gz` for paired-end reads, and add workflow-specific flags such as `--rrbs`, `--fastqc`, `--cores`, `--poly_a`, or explicit adapter specifications. Trim Galore writes trimmed FASTQ files and per-input trimming reports. The v2 documentation also describes structured JSON reports for MultiQC and an in-process FastQC-compatible reporting path. ### Warum Paket-Nerds sich dafür interessieren Trim Galore matters to package-manager users because it sits at the boundary between classic scientific scripting and modern single-binary distribution. The old Perl-era package pulled together Perl, Python/Cutadapt, Java/FastQC, and compression tools; the v2 rewrite turns the same familiar CLI into a Rust binary with no runtime dependencies. For reproducible bioinformatics environments, it is notable that the official install page now supports multiple packaging cultures: Cargo/crates.io, Bioconda, Docker via GitHub Container Registry, source builds, and release binaries, while distro/package-manager metadata in the input shows Homebrew, Debian, and Ubuntu coverage. ### Zeitleiste - 2012: Official changelog lists v0.1.3 on 14 Mar 2012 and v0.1.4 on 21 Mar 2012. - 2013: v0.3.x releases expanded the early Perl wrapper line. - 2019: v0.6.0 was released on 1 Mar 2019. - 2021: v0.6.7 was released to obtain a Zenodo DOI. - 2026: v0.6.11 was released on 24 Feb 2026. - 2026: v2.x introduced the Rust rewrite as a single static binary and drop-in successor to v0.6.x. ### Related projects - Cutadapt was the adapter-trimming engine wrapped by the historical Perl Trim Galore implementation. - FastQC provided external quality-control reports in the older workflow; v2 integrates FastQC-compatible reporting through fastqc-rust. - MultiQC is relevant because Trim Galore reports, including v2 JSON reports, are intended for aggregation in sequencing QC workflows. ### Quellen - - - - - - - - source_facts.package-manager ## Sicherheitshinweise Für trim-galore wurde kein passendes lokales Secret-Handling-Manifest gefunden. Nucleus-Paketmetadaten bleiben hier veröffentlicht, damit künftige Abdeckung eine stabile Paket-URL hat. ## Andere Paketmanager-Einträge - Debian apt - trim-galore - 0.6.10-1: normalized package name match | Debian stable package indexes: trim-galore from https://deb.debian.org/debian/dists/stable/main/binary-amd64/Packages.xz | automate quality and adapter trimming for DNA sequencing | https://www.bioinformatics.babraham.ac.uk/projects/trim_galore/ - Ubuntu apt - trim-galore - 0.6.10-1: normalized package name match | Ubuntu 24.04 LTS package indexes: trim-galore from https://archive.ubuntu.com/ubuntu/dists/noble/universe/binary-amd64/Packages.gz | automate quality and adapter trimming for DNA sequencing | https://www.bioinformatics.babraham.ac.uk/projects/trim_galore/ ## Combined YAML source View the package source record on GitHub. [combined/trim-galore.yml](https://github.com/mxcl/pkgdb/blob/main/combined/trim-galore.yml) ## Quellen - pkg.so package database - curated package history - pkgdb category and tag curation - external package-manager database matches - cross-ecosystem install command graph