# miniprot mit Homebrew installieren

Prüfe Installationswege, Executables, Metadaten und Sicherheitshinweise für miniprot in AI-Agent-Workflows.

## Installation

```sh
sudo av install brew:miniprot
```

Weitere Installationsbefehle:

### macOS

- Homebrew (100%):

```sh
brew install miniprot
```

  Evidenz: local Homebrew formula metadata

## Paketfakten

- **Paketschlüssel:** brew:miniprot
- **Paketmanager:** Homebrew
- **Version:** 0.18
- **Quellzusammenfassung:** Align proteins to genomes with splicing and frameshift
- **Homepage:** <https://lh3.github.io/miniprot/>
- **Repository:** <https://github.com/lh3/miniprot>
- **Generiert:** 2026-08-03T19:37:03+00:00

## Executables

- miniprot (Alias)

## Installationsverhalten

- Bottle: nicht verfügbar

## Version und Aktualität

- Seite generiert: 2026-08-03
- Manager-Version: 0.18
## Projektgeschichte und Nutzung

miniprot is Heng Li's protein-to-genome aligner for genome annotation. The preprint appeared in 2022 and the Bioinformatics paper was published in 2023, describing miniprot as a new aligner for mapping protein sequences to complete genomes with k-mer sketching and vectorized dynamic programming.

### Projektgeschichte

The program fills a bioinformatics gap between older tools such as GeneWise and Exonerate and the scale of modern genome projects. Its README says it aligns protein sequences against genomes with affine gap penalties, splicing, and frameshifts, primarily to annotate protein-coding genes in a new species using known genes from other species. It can build a genome index, output protein PAF, emit GFF3 with embedded PAF, and optionally use splice scores from minisplice.

### Wie es verwendet wird

Adoption is source-backed through bioinformatics workflows rather than general-purpose package popularity. BUSCO's user guide lists miniprot among third-party tools to cite, and the GALBA genome-annotation pipeline paper describes genome annotation with miniprot and AUGUSTUS. Homebrew packages it as a single `miniprot` executable for the scientific-command-line niche, alongside Bioconda-style distribution and upstream source builds.

### Quellen

- <https://arxiv.org/abs/2210.08052>
- <https://busco.ezlab.org/busco_userguide.html>
- <https://doi.org/10.1186/s12859-023-05449-z>
- <https://formulae.brew.sh/formula/miniprot>
- <https://github.com/lh3/miniprot>
- <https://lh3.github.io/miniprot/miniprot.html>
- <https://pubmed.ncbi.nlm.nih.gov/36648328/>


## Sicherheitshinweise

narrow executable package without higher-risk signals.

- **Geiger-Risiko:** grün / niedrig
- narrow executable package without higher-risk signals


## Combined YAML source

View the package source record on GitHub. [combined/miniprot.yml](https://github.com/mxcl/pkgdb/blob/main/combined/miniprot.yml)


## Quellen

- pkg.so package database
- Geiger risk classifier
- curated package history
- pkgdb category and tag curation
- cross-ecosystem install command graph