macOS
brew install minibwalocal Homebrew formula metadata
brew / rank 10313
Successor of BWA-MEM for short-read alignment. Version 0.6 via Homebrew; verified 2026-07-30.
install
brew install minibwalocal Homebrew formula metadata
overview
Successor of BWA-MEM for short-read alignment
history
minibwa is a genomic read aligner from the BWA/minimap2 lineage. The repository identifies it as the successor of BWA-MEM for short-read alignment, and the arXiv preprint by Heng Li and Nils Homer presents it as a next iteration of BWA-MEM for standard whole-genome short reads, Hi-C reads, accurate long reads, and directional bisulfite sequencing data.
The design deliberately mixes earlier tools by the same lineage: a BWA-MEM-style BWT/FM-index and variable-length seed search, ropebwt3-inspired supermaximal exact-match work, and minimap2-style chaining plus SIMD-based base alignment. The authors report comparable accuracy with much higher speed than BWA-MEM and BWA-MEM2, while noting that exact BWA-MEM compatibility is traded for algorithmic improvement.
In practice, minibwa is a bioinformatics command-line aligner for pipelines that map sequencing reads to a reference genome before variant calling, methylation analysis, or related downstream analysis. Its package-manager niche is narrow but important: it gives genomics users an installable replacement candidate for BWA-MEM where performance and support for newer read types matter more than byte-for-byte legacy output.
security posture
No matching local secret-handling manifest was found for minibwa. Package metadata is still published here so future coverage has a stable package URL.
Before unattended agent use, check whether the tool reads plaintext credentials, writes remote state, publishes artifacts, or shells out to plugins.
executables
| Command | Kind | Exposure | Note |
|---|---|---|---|
minibwa | cli | global executable |
freshness
These signals separate page generation age, package-manager activity, and upstream release comparison. Version lag is warned only when an evidence URL and comparable versions are present.
https://github.com/lh3/minibwa
install metadata
| Package key | brew:minibwa |
|---|---|
| Version | 0.6 |
| Package manager | Homebrew |
| Package manager page | https://formulae.brew.sh/formula/minibwa |
| Homepage | https://github.com/lh3/minibwa |
| Repository | https://github.com/lh3/minibwa |
| License | MIT AND Apache-2.0 |
| Source archive | https://github.com/lh3/minibwa/archive/refs/tags/v0.6.tar.gz |
| Last updated | 2026-07-30T15:48:22Z |
| Pulse | updated |
| Bottle | available (on arm64_linux, arm64_sequoia, arm64_sonoma, arm64_tahoe, sonoma, x86_64_linux) |
| Homebrew post-install | not defined |
| Service | none declared |
registry facts
| Source Database | Homebrew formula API |
|---|---|
| Tap | homebrew/core |
| Full Name | minibwa |
| Version Scheme | 0 |
| Revision | 0 |
| Bottle Stable Root URL | https://ghcr.io/v2/homebrew/core |
| Deprecated | no |
| Disabled | no |
| Keg Only | no |
| URL Keys |
|
source trail
This page is generated by av-web from the private package SQLite artifact built by scripts/generate-pkg-sqlite.py.
View the package source record on GitHub.